USA Weekend Trips: 20 Incredible Destinations for a Quick Escape

Nestled in the Blue Ridge Mountains, Asheville is a haven for nature lovers and culture enthusiasts alike.

What to Do: Explore the majestic Biltmore Estate, hike in the surrounding mountains, and indulge in the thriving craft beer scene.

Where to Stay: The Omni Grove Park Inn offers stunning mountain views and a world-class spa.

Immerse yourself in the artistic community and stunning landscapes of Taos.

What to Do: Visit Taos Pueblo, explore the Rio Grande Gorge, and browse the many art galleries.

Where to Stay: El Monte Sagrado offers luxurious accommodations inspired by Native American culture.

Experience the unique culture, music, and cuisine of the Big Easy.

What to Do: Explore the French Quarter, take a jazz cruise on the Mississippi River, and indulge in beignets at Café du Monde.

Where to Stay: Hotel Monteleone, a historic hotel in the heart of the French Quarter, famous for its rotating Carousel Bar.

Escape to this tranquil archipelago in the Pacific Northwest for a peaceful weekend retreat.

What to Do: Go whale watching, kayaking, and explore the charming town of Friday Harbor.

Where to Stay: Friday Harbor House offers cozy rooms with stunning harbor views.

Experience quintessential New England charm in this picturesque mountain town.

What to Do: Ski at Stowe Mountain Resort, hike the Stowe Pinnacle Trail, and tour the Ben & Jerry's Factory.

Where to Stay: The Lodge at Spruce Peak offers ski-in/ski-out luxury accommodations.

Nature lovers will be in awe of the pristine wilderness and majestic mountains of Glacier National Park.

What to Do: Drive the Going-to-the-Sun Road, hike to Hidden Lake, and spot wildlife like mountain goats and grizzly bears.

Where to Stay: Many Glacier Hotel, a historic Swiss-style lodge on the shores of Swiftcurrent Lake.

For a tropical weekend without leaving the continental US, Key West is hard to beat.

What to Do: Visit Ernest Hemingway's home, watch the sunset at Mallory Square, and go snorkeling in crystal-clear waters.

Where to Stay: Ocean Key Resort & Spa offers luxury accommodations with stunning Gulf of Mexico views.

Whether you visit in winter for skiing or summer for hiking, Aspen offers year-round appeal.

What to Do: Hit the slopes, hike Maroon Bells, and enjoy the town's high-end shopping and dining.

Where to Stay: The Little Nell, Aspen's only five-star, five-diamond hotel, offers ski-in/ski-out access.

Wine enthusiasts will love a weekend in this world-renowned wine region.
What to Do: Visit wineries for tastings, take a hot air balloon ride, and dine at Michelin-starred restaurants.
Where to Stay: Auberge du Soleil offers luxurious accommodations with stunning valley views.

Immerse yourself in Southern hospitality and history in this charming coastal city.

What to Do: Take a horse-drawn carriage tour, visit historic plantations, and enjoy low country cuisine.

Where to Stay: The Spectator Hotel offers 1920s-inspired luxury in the heart of the historic district.

Known for its stunning red rock formations and spiritual vortexes, Sedona is perfect for a rejuvenating weekend.

What to Do: Hike the numerous trails, take a Pink Jeep Tour, and relax with a spa treatment.

Where to Stay: L'Auberge de Sedona offers creek-side cottages and red rock views.

Step back in time on this car-free island in Lake Huron, known for its Victorian charm.
What to Do: Bike around the island, visit historic Fort Mackinac, and indulge in world-famous Mackinac Island fudge.
Where to Stay: The Grand Hotel, a historic landmark with the world's longest porch, offers a truly grand experience.

For outdoor enthusiasts, Moab serves as the perfect base for exploring two stunning national parks.
What to Do: Hike in Arches National Park, go mountain biking, and take a scenic drive through Canyonlands National Park.
Where to Stay: Under Canvas Moab offers a unique glamping experience surrounded by red rock landscapes.

Experience Gilded Age opulence and coastal beauty in this historic New England town.

What to Do: Tour the magnificent Newport Mansions, walk the scenic Cliff Walk, and enjoy fresh seafood at the waterfront.

Where to Stay: The Chanler at Cliff Walk offers luxurious accommodations with ocean views.

This quaint coastal town offers a perfect blend of natural beauty and artistic charm.

What to Do: Stroll through the fairytale-like downtown, relax on Carmel Beach, and visit nearby Point Lobos State Natural Reserve.

Where to Stay: L'Auberge Carmel, a Relais & Châteaux property, offers European-style luxury in the heart of town.

Adventure seekers will find plenty to love in this mountain town gateway to Grand Teton National Park.

What to Do: Go skiing or snowboarding in winter, hike in summer, and take a scenic gondola ride for breathtaking views.

Where to Stay: The Rusty Parrot Lodge offers luxury accommodations with a rustic touch.

Step back in time in this charming Southern city known for its antebellum architecture and Spanish moss-draped trees.

What to Do: Take a ghost tour, picnic in Forsyth Park, and explore the historic district's beautiful squares.

Where to Stay: The Kehoe House, a beautifully restored 1892 Renaissance Revival mansion.

Immerse yourself in the rich cultural tapestry and artistic spirit of Santa Fe.

What to Do: Visit the Georgia O'Keeffe Museum, explore the historic Plaza, and experience the unique blend of Native American and Spanish cultures.

Where to Stay: La Fonda on the Plaza, a historic hotel with authentic Southwestern decor.

For a taste of New England charm and breathtaking coastal scenery, Bar Harbor is hard to beat.

What to Do: Explore Acadia National Park, take a whale watching tour, and indulge in fresh lobster.

Where to Stay: The Bar Harbor Inn & Spa offers oceanfront rooms and easy access to downtown.

This Texan gem blends rich history with modern attractions, making it perfect for a weekend trip.

What to Do: Visit the historic Alamo, stroll along the charming River Walk, and enjoy Tex-Mex cuisine at the bustling Market Square.

Where to Stay: Hotel Emma, a former 19th-century brewery turned luxury hotel, offers a unique stay in the heart of the city.