Sudden, unintentional weight loss of 10 pounds (4.5 kg) or more over 6-12 months without changes in diet or exercise. This can be a sign of various cancers, particularly those affecting the digestive system such as pancreatic, stomach, esophageal, or lung cancer. Weight loss occurs as cancer cells consume the body’s energy supply and alter metabolism.
Treatment:
- Identify and treat the underlying cause (cancer or otherwise)
- Nutritional counseling and support
- High-calorie, nutrient-dense diet
- Appetite stimulants like megestrol acetate or dronabinol if necessary
- Enteral or parenteral nutrition in severe cases
- Address any psychological factors affecting appetite
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